Protein degradation is essential for maintaining cellular homeostasis.The proteasome is the centralenzyme responsible for non-lysosomal protein degradation in eukaryotic cells.Although proteasome assembly is not yet completelyunderstood, a number of cofactors required for proper Tools assembly and maturation have been identified.Ump1 is a short-liv
As required by regulations, Finite Wax Melts Element Analyses (FEA) can be used to investigate the behavior of joints which might be complex to design due to the presence of geometrical and material discontinuities.The static behavior of such problems is mesh dependent, thus these results must be calibrated by using laboratory tests or reference da
In the Noctuidae, the owlet moths, the internal genitalia, i.e.the aedeagus and vesica (penis) in the males, and the bursa copulatrix in the females, together form a lock-and-key mechanism (LKM).The species-specific structures have their counterparts in the opposite sex.The internal LKM constitutes a specific reproductive isolation mechanism (lock-
Spanish science in exile operated as a network of networks.Its dynamics help us understand the deep imprint that exiled scientists left in their host countries.The network was characterized by its tendency to maintain links that 5-HTP had existed before the Spanish Civil War and the establishment of alliances with multiple actors, not just humans,
Complete staghorn renal calculi are surgical challenge requiring multi-tract or staged PCNL.We report a case of supine PCNL where Cholesterol Synthesis complete stone clearance was achieved with dual tracts (24 Fr/lower pole and 16Fr/upper pole) through which two surgeons operated simultaneously using two different energy sources (pneumatic/ultraso